ST Alpha - "The GSK anit-smoking drug is just an anti-depressant (Wellbutrin) under a different name (Zyban)? -- nm" (Reading a Post)

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In response to "Geesh, first acetaminophen, now this. FDA warning on anti-smoking drugs.. -- (link)" by MojaveMeg

The GSK anit-smoking drug is just an anti-depressant (Wellbutrin) under a different name (Zyban)? -- nm

Posted by ty97 Jul 1 '09, 18:52

(No message)

Responses:

Yeah, same product. -- nm - Tim Jul 1, 18:53 14
- I had no idea. I figured the drug was some sort of low-dose nicotine replacement or something - ty97 Jul 1, 18:54 13
  - Basically, people taking it for depression noticed that their nicotine cravings went away. Surprise side effect. -- nm - loosilu Jul 1, 18:56 12
    - Not the first drug where that's happened. - Tim Jul 1, 18:59 5
      - Viagra was first planned as a heart pill. When they went to get the samples back from the participants, they wouldn't give them up. -- nm - Reagen Jul 1, 19:03 1
        
        There is a drug called Revatio that is the same thing as Viagra and indicated for pulmonary hypertension. - Tim Jul 1, 19:07
      - I can sorta see this one -- nm - ty97 Jul 1, 19:00
      - I was hoping you'd pop up here. -- nm - loosilu Jul 1, 18:59 1
        
        Oh man I missed pharmacy discussion in the day! (when I was working, obvie) (nm) - Tim Jul 1, 19:52
    - odd, but fair enough - ty97 Jul 1, 18:57 5
      - Actually it makes a lot of sense, chemically. Nicotine affects the same neurotransmitters as Wellbutrin. - loosilu Jul 1, 18:59
      - oh, they were thrilled. Not sure how they found Chantix. might be similar. -- nm - loosilu Jul 1, 18:58 3
        
        Chantix is a new compound, not related to anti-depressants. -- nm - Tim Jul 1, 19:00 2
        
        was it developed specifically for this purpose? -- nm - loosilu Jul 1, 19:00 1
        
        Looks like they were mucking around with a product used only in europe for smoking cessation and Chantix was derived from it. -- nm - Tim Jul 1, 19:02
yeah, it's known to cause seizures. I haven't looked at the warning yet. -- nm - loosilu Jul 1, 18:53 2
- the warning is increased risk of suicide, which is common (I think) with anti-depressants, at the early stages as they build up. -- nm - ty97 Jul 1, 18:54 1
  - oh, I see. I never know what to think of tthat effect, since the drugs are given to people who may already be suicidal. -- nm - loosilu Jul 1, 18:55

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