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The preliminary sequence from the H5N1 human case in British Columbia has been posted and it is not good news. The virus potentially has a quasispecies at HA residue 226 (H3 numbering). This is bad news because we know that mutations at residue 226 can increase binding to human receptors. 1/ — Hensley Lab (@scottehensley.bsky.social) 2024-11-16T15:19:32.430Z
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